In Which Situations IVF Treatment Preferred?

Some of the reasons behind the need for IVF Treatment are as follows:

Fallopian tube damage or obstruction: Damage or obstruction of the fallopian tube makes it difficult for an egg to fertilize or for an embryo to travel to the uterus.

Ovulation disorders: Low ovarian reserve Anovulation accounts for 5-25% of infertility causes. Whether a woman is ovulating or not can be detected by monitoring ovulation with ultrasonography (USG) or by looking at the progesterone hormone levels in the serum (on the 19th, 21st and 23rd days of the menstrual cycle). In the USG, the egg does not grow or the repetitive progesterone measurements are below 3 mg/ml, indicating that there is no ovulation.

Endometriosis: Endometriosis occurs when uterine tissue settles and grows outside of the uterus – often affecting the function of the ovaries, uterus, and fallopian tubes.

Uterine fibroids: Fibroids are benign tumors in the wall of the uterus and are common in women in their 30s and 40s. Fibroids can interfere with the implantation of the fertilized egg.

Previous tubal sterilization or removal: If you have had tubal ligation (a type of sterilization in which the fallopian tubes are cut or blocked to permanently prevent pregnancy) and you want to conceive, IVF tubal ligation may be an alternative to reversing this situation.

Impaired sperm production or function: Below-average sperm concentration, poor motility of sperm (poor motility), inability to penetrate the cervical mucus, inability to survive, or abnormalities in sperm size and shape.

Unexplained infertility: Unexplained infertility means no cause of infertility has been found despite evaluation for common causes.

A genetic disorder: If there is a risk of passing the genetic disorder to their children, mothers and fathers can apply for preimplantation genetic tests. In IVF treatment, after the eggs are collected and fertilized, they are screened for some genetic problems; but not all genetic problems can be found. Embryos without identified genetic defects can be transferred to the uterus. Preimplantation genetic diagnosis (PGD) is a diagnostic method recommended for couples who are at risk of transmitting a serious genetic disease to their children. In the embryos of couples who have some genetic diseases such as cystic fibrosis and thalassemia, the disease can be diagnosed and the embryo can be eliminated in this way before pregnancy occurs, without the need to terminate the pregnancy, thanks to PGD. Preimplantation genetic diagnosis offers an alternative way not only for couples at risk of such genetic diseases, but also for couples who are unable to produce a healthy pregnancy due to recurrent miscarriages caused by structural chromosomal disorders (eg, translocation, inversion, etc.).

Fertility preservation for cancer or other health conditions: If you are about to start treatment for cancer, such as radiotherapy or chemotherapy that can harm fertility, IVF for fertility preservation may be a good option. Because with the in vitro fertilization method, women can collect eggs from their ovaries and freeze them in an unfertilized state for later use. Alternatively, eggs can be fertilized and frozen as embryos for future use.

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